Innovation in KLEx Surgery

13 Dec 2025 09:15 09:35
呂宥萱 Yu-Hsuan LuTaiwan Speaker Innovation in KLEx SurgeryKeratorefractive Lenticule Extraction (KLEx) continues to evolve as a leading minimally invasive approach for corneal refractive correction. Among emerging technologies, Johnson & Johnson Vision’s Smooth Incision Lenticule Keratomileusis (SILK) represents a significant advancement within the KLEx family by addressing key limitations of earlier lenticule-based procedures. SILK is engineered around three core innovations: exceptionally low pulse energy, smooth continuous dissection, and a biconvex lenticule design. SILK operates at an ultralow pulse energy of approximately 50 nJ, one of the lowest among current refractive laser platforms. This reduced energy delivery minimizes collateral stromal disruption, promotes cleaner interface quality, and may decrease postoperative inflammation. Complementing this, SILK utilizes a smooth, continuous dissection pattern that creates highly uniform cleavage planes. This design facilitates gentle lenticule separation and extraction through a micro-incision, reducing mechanical stress on the cornea and supporting rapid early visual recovery. A further distinguishing feature is the biconvex lenticule configuration, which improves its natural conformability to the stromal bed and reduces interface mismatch. This enhanced anatomical fit may help preserve subbasal corneal nerves during tissue creation and extraction, thereby lowering the risk of postoperative dry eye symptoms and supporting overall ocular surface health. Together, these innovations position SILK as a refined next-generation KLEx technique with strong potential in clinical practice. Ongoing investigations comparing the strengths and limitations of different KLEx approaches will continue to guide technique optimization, with the ultimate goal of providing patients with the safest and most effective refractive surgical outcomes.